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{"id":7470,"date":"2020-04-23T10:29:58","date_gmt":"2020-04-23T13:29:58","guid":{"rendered":"http:\/\/www.apufsc.org.br\/?p=7470"},"modified":"2020-04-23T10:29:59","modified_gmt":"2020-04-23T13:29:59","slug":"coronavirus-pode-deixar-sequelas-neurologicas-graves-alertam-cientistas-brasileiros","status":"publish","type":"post","link":"https:\/\/www.apufsc.org.br\/2020\/04\/23\/coronavirus-pode-deixar-sequelas-neurologicas-graves-alertam-cientistas-brasileiros\/","title":{"rendered":"Coronav\u00edrus pode deixar sequelas neurol\u00f3gicas graves, alertam cientistas brasileiros"},"content":{"rendered":"\n

Dist\u00farbios como convuls\u00f5es e desorienta\u00e7\u00e3o sofridos por doentes com Covid 19 sinalizam ataque do v\u00edrus ao c\u00e9rebro<\/h4>\n\n\n\n

Cientistas do\u00a0Rio de Janeiro\u00a0e do\u00a0Canad\u00e1\u00a0alertam que entre os impactos de longo prazo da pandemia do coronav\u00edrus podem estar\u00a0doen\u00e7as neurol\u00f3gicas\u00a0<\/strong>e\u00a0neurodegenerativas. Num estudo publicado na edi\u00e7\u00e3o de hoje da revista Trends in Neurosciences, o grupo de pesquisadores da Universidade Federal do Rio de Janeiro (UFRJ), do Instituto D\u2019Or de Pesquisa e Educa\u00e7\u00e3o (Idor) e da\u00a0Universidade Queen\u2019s, no Canad\u00e1, analisam os casos de complica\u00e7\u00f5es neurol\u00f3gicas observadas em pacientes com Covid-19\u00a0 e advertem para a necessidade de investigar as poss\u00edveis sequelas nos sobreviventes.<\/p>\n\n\n\n

Os dist\u00farbios sofridos por alguns\npacientes incluem convuls\u00f5es, perda de consci\u00eancia, derrames, encefalite,\ndesorienta\u00e7\u00e3o e indicam que a Covid-19 pode atacar o c\u00e9rebro. Os pesquisadores,\npor\u00e9m, n\u00e3o sabem ainda se os danos s\u00e3o causados pelo ataque direto do\nv\u00edrus Sars-CoV-2<\/strong>, se pela rea\u00e7\u00e3o inflamat\u00f3ria generalizada\nprovocada por ele (a chamada tempestade imunol\u00f3gica) ou se pela combina\u00e7\u00e3o de\nambos. O fato \u00e9 que doentes de Covid-19 t\u00eam apresentado dist\u00farbios\nneurol\u00f3gicos, que potencialmente pode deixar sequelas.<\/p>\n\n\n\n

\u201cO coronav\u00edrus tem nos\nsurpreendido, age de forma estranha. A Covid-19 est\u00e1 longe de ser apenas uma\ndoen\u00e7a respirat\u00f3ria. \u00c9 preciso acompanhar os sobreviventes e avaliar se\ndesenvolvem sintomas de dist\u00farbios neurol\u00f3gicos\u201d, destaca a neurocientista\nFernanda De Felice, da UFRJ e da Universidade Queen\u2019s.<\/p>\n\n\n\n

O tamb\u00e9m neurocientista Sergio\nFerreira, da UFRJ, diz que as les\u00f5es observadas em algumas v\u00edtimas de Covid-19\nse assemelham \u00e0quelas associadas a doen\u00e7as neurodegenerativas. S\u00e3o doen\u00e7as\nneurodegenerativas, por exemplo, os males de Alzheimer e de Parkinson.<\/p>\n\n\n\n

Biomarcadores<\/strong><\/p>\n\n\n\n

Os\npesquisadores se preparam agora para iniciar um amplo estudo no Brasil sobre o\nimpacto do coronav\u00edrus no sistema nervoso e tamb\u00e9m buscar subst\u00e2ncias no sangue\nque possam indicar o risco de ataque da Covid-19 ao sistema nervoso central.\nDentre outras coisas, buscam identificar poss\u00edveis biomarcadores de\ncomprometimento neurol\u00f3gico na Covid-19.<\/p>\n\n\n\n

\u201cBiomarcadores\ns\u00e3o a necessidade mais urgente e ser\u00e3o instrumentos preciosos para os m\u00e9dicos\navaliarem a gravidade do estado dos pacientes e poderem intervir logo. Tamb\u00e9m\najudar\u00e3o a identificar o risco de sequelas\u201d, diz Fernanda Tovar Moll, do Idor e\nda UFRJ.<\/p>\n\n\n\n

Esse\nestudo dever\u00e1 ser feito por um cons\u00f3rcio de pesquisa do IDOR com universidades\ne hospitais p\u00fablicos e investigar dados de mais de 2.000 casos de pessoas infectadas\npelo coronav\u00edrus.<\/p>\n\n\n\n

O\nneurocientista Jorge Moll, do Idor, diz que os pesquisadores correm para\nentender como acontece o agravamento da Covid-19.  Os cientistas\nsabem que coronav\u00edrus de forma geral, e n\u00e3o apenas o Sars-CoV-2, s\u00e3o\nneurotr\u00f3picos. Isso significa que t\u00eam particular atra\u00e7\u00e3o por c\u00e9lulas nervosas.\nMas n\u00e3o conhece ainda o qu\u00e3o neurotr\u00f3pico o Sars-CoV-2 \u00e9.<\/p>\n\n\n\n

Os\ncientistas tamb\u00e9m investigam como o novo coronav\u00edrus poderia chegar ao c\u00e9rebro.\nUma possibilidade \u00e9 que o nariz seja principal a porta de entrada do\ncoronav\u00edrus para o c\u00e9rebro. A perda de olfato frequente em pessoas com Covid-19\ntem sido associada ao ataque do coronav\u00edrus ao nervo olfat\u00f3rio. Cientistas\nsabem que outros v\u00edrus podem usar o nervo olfat\u00f3rio para alcan\u00e7ar o c\u00e9rebro.<\/p>\n\n\n\n

Outra possibilidade, explica Sergio\nFerreira, \u00e9 que o v\u00edrus chegue ao c\u00e9rebro por meio da microcircula\u00e7\u00e3o\nsangu\u00ednea. Essa seria uma forma de romper a barreira hematoencef\u00e1lica que\nprotege o c\u00e9rebro do pat\u00f3genos.<\/p>\n\n\n\n

\u201cN\u00e3o sabemos o que est\u00e1 acontecendo dentro do c\u00e9rebro dos pacientes. E precisamos descobrir logo\u201d, diz Jorge Moll. <\/p>\n\n\n\n

O Globo<\/a><\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"

Dist\u00farbios como convuls\u00f5es e desorienta\u00e7\u00e3o sofridos por doentes com Covid 19 sinalizam ataque do v\u00edrus ao c\u00e9rebro […]<\/a><\/p>\n<\/div>","protected":false},"author":12,"featured_media":5640,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[549],"tags":[893,1247],"class_list":{"0":"post-7470","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-o-globo","8":"tag-cientistas","9":"tag-pandemia"},"featured_image_src":"https:\/\/www.apufsc.org.br\/wp-content\/uploads\/2020\/03\/coronavirus-600x322.jpg","featured_image_src_square":"https:\/\/www.apufsc.org.br\/wp-content\/uploads\/2020\/03\/coronavirus-600x322.jpg","author_info":{"display_name":"Imprensa Apufsc","author_link":"https:\/\/www.apufsc.org.br\/author\/apufsc\/"},"_links":{"self":[{"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/posts\/7470"}],"collection":[{"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/comments?post=7470"}],"version-history":[{"count":1,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/posts\/7470\/revisions"}],"predecessor-version":[{"id":7471,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/posts\/7470\/revisions\/7471"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/media\/5640"}],"wp:attachment":[{"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/media?parent=7470"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/categories?post=7470"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.apufsc.org.br\/wp-json\/wp\/v2\/tags?post=7470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}